After graduating from Charing Cross Hospital, Dr. Goldstone worked at St Thomas’, Kings College and the Brompton Hospitals. He completed his MD thesis at the Respiratory Muscle Laboratory of the Brompton and Kings College Hospitals under the supervision of Professor Malcolm Green and Professor John Moxham. He returned to Clinical Medicine at University College London, and was appointed a Clinical Senior Lecturer/ Consultant in 1991, based at the Middlesex Hospital. Over the next 5 years he established the foundations for the Centre for Anaesthesia at UCL, which during this time the Department was successful in obtaining the first Welcome grant and created the first successful PhD fellowship. His clinical interests have included the science and physiology of weaning from mechanical ventilation, the bedside measurement of blood flow to the brain and the prediction of mortality before high risk surgery. He became a full time Consultant at University College Hospital in 2001. He now spends his clinical time within the Intensive Care Unit, teaching and training undergraduates and junior doctors. He was appointed as Clinical Director for Intensive Care Medicine at The London Clinic in 2002, and has additionally undertaken several management roles.